Pentoxifylline and vitamin E drug compliance after adjuvant breast radiation therapy

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Pentoxifylline and vitamin E drug compliance after adjuvant breast radiation therapy

Purpose Breast fibrosis is a common late effect after therapeutic irradiation that can result in pain, poor cosmesis, and functional impairment. Randomized trials have demonstrated that radiation fibrosis may be preventable with a medication regimen of pentoxifylline and vitamin E. This study investigates patient compliance with pentoxifylline therapy while examining possible correlations to co...

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Is pentoxifylline plus vitamin E effective for treatment of radiation-induced fibrosis (RIF)?

Late or chronic fibrosis of soft tissues represents a serious and common complication of radiation therapy in the treatment of malignancy.1,2 Few treatment modalities exist for managing RIF.2 Pentoxifylline, a methylxanthine derivative approved by the Food and Drug Administration for the treatment of patients with intermittent claudication, is one of the first medications available in the US th...

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ژورنال

عنوان ژورنال: Advances in Radiation Oncology

سال: 2018

ISSN: 2452-1094

DOI: 10.1016/j.adro.2017.09.004